Publications

General review on mesoporous silica for drug delivery. 

 1. Mesoporous ASD: Fundamentals 

Garcia-Bennett, Alfonso ; Feiler, Adam 

Amorphous Solid Dispersions: Theory and Practice, pp.637-663 

NLAB silica loaded with APIs Clofazaime for treatment of tuberculosis (TB) and coatings 

2. Clofazimine encapsulation in nanoporous silica particles for the oral treatment of antibiotic resistant M. tuberculosis infections 

Valetti, Sabrina ; Xia, Xin ; Costa-Gouveia, Joana ; Brodin, Priscille ; Bernet-Camard, Marie-Françoise ; Andersson, Margareta ; Feiler, Adam 

Nanomedicine, 2017, Vol.12(8) 

3. Cyclodextrin-mesoporous silica particle composites for controlled antibiotic release. A proof of concept toward colon targeting 

Stjern, Louise ; Voittonen, Sandra ; Weldemichel, Rahel ; Thuresson, Sofia ; Agnes, Marco ; Benkovics, Gabor ; Fenyvesi, Éva ; Malanga, Milo ; Yannakopoulou, Konstantina ; Feiler, Adam ; Valetti, Sabrina 

International Journal of Pharmaceutics, 15 October 2017, Vol.531(2), pp.595-605 

4. Mesoporous silica particles as a lipophilic drug vehicle investigated by fluorescence lifetime imaging 

Valetti, Sabrina ; Wankar, Jitendra ; Ericson, Marica B. ; Feiler, Adam ; Manet, Ilse 

Journal of Materials Chemistry B, 2017, Vol.5(17), pp.3201-3211 

5. Fluorescence imaging of antibiotic clofazimine encapsulated within mesoporous silica particle carriers: relevance to drug delivery and the effect on its release kinetics 

Angiolini, Lorenzo ; Valetti, Sabrina ; Cohen, Boiko ; Feiler, Adam ; Douhal, Abderrazzak 

Physical Chemistry Chemical Physics, 2018, Vol.20(17), pp.11899-11911 

NLAB silica particles for cancer therapy loaded with folic acid and cisplatin and Nitric oxide precursor   

6. Targeted Photodynamic Therapy with a Folate/Sensitizer Assembly Produced from Mesoporous Silica 

Zhou, Chunfang ; Afonso, Damien ; Valetti, Sabrina ; Feiler, Adam ; Cardile, Venera ; Graziano, Adriana C. E. ; Conoci, Sabrina ; Sortino, Salvatore 

Chemistry – A European Journal, 07 June 2017, Vol.23(32), pp.7672-7676 

7. Multivalent mesoporous silica nanoparticles photo-delivering nitric oxide with carbon dots as fluorescence reporters  

Afonso, Damien ; Valetti, Sabrina ; Fraix, Aurore ; Bascetta, Claudia ; Petralia, Salvatore ; Conoci, Sabrina ; Feiler, Adam ; Sortino, Salvatore 

Nanoscale, 2017, Vol.9(36), pp.13404-13408 

NLAB silica loaded with peptides and trophic factors  

8. Delivery of Differentiation Factors by Mesoporous Silica Particles Assists Advanced Differentiation of Transplanted Murine Embryonic Stem Cells 

Alfonso E. Garcia-Bennett, A,B, Mariya Kozhevnikova, C, Niclas König, C, Chunfang Zhou, B Richardson Leao, C Thomas Knöpfel, D Stanislava Pankratova, E Carl Trolle, C Vladimir Berezin, E Elisabeth Bock, E Håkan Aldskogius, C Elena N. Kozlova 

STEM CELLS TRANSLATIONAL MEDICINE 2013;2:906–915 

Empty particles sequestering toxic agents for neurodegenerative disease. 

9. Empty mesoporous silica particles significantly delay disease progression and extend survival in a mouse model of ALS 

Marcel F. LeytonJaimes, Patrik Ivert, Jan Hoeber, Yilin Han, Adam Feiler, Chunfang Zhou, Stanislava Pankratova, Varda ShoshanBarmatz, Adrian Israelson, Elena N. Kozlova 

Scientifc Reports  (2020) 10:20675 

Fundamental properties of silica particles 

10. Bare and Effective Charge of Mesoporous Silica Particles 

Valetti, Sabrina ; Feiler, Adam ; Trulsson, Martin Langmuir

ACS journal of surfaces and colloids, 25 July 2017, Vol.33(29), pp.7343-7351