Drug Development

Business Area Drug Development

In drug development, Nanologica focuses on inhaled drugs and respiratory diseases, where the company develops a drug delivery platform. The technology is based on APIs (active pharmaceutical ingredients) being placed inside the pores of nanoporous amorphous silica particles, NAPs™, which act as carrier particles to deliver the API to the lung. Formulation with NAP™ takes aim at improving the solubility and bioavailability of APIs and protect substances from degradation. The drug loaded particles can then be formulated as a powder for inhalation and are aerosolized from commercially available dry powder inhalers. After the API is released into the lung, the carrier particles shall be dissolved and eliminated.

 

By reformulating clinically proven APIs into inhaled formulations, Nanologica has the potential to improve patients’ quality of life and/or enable local treatment to the lung where today only systemic treatment is available. The goal is to provide a platform technology that enables improved or completely new treatments for patients with severe lung diseases.

Dissolution of API loaded into NLAB Silica™

Nanologica’s drug delivery technology  is tailormade for  inhalation. The size of the nanoporous microspheres is between 2 to 5 µm and tailored to reach the desired part of the lung – the smaller particles, the further into the lung the particle containing the API can reach.  

Nanologica’s business model includes licensing agreements/ technology transfer, feasibility studies, fee for service contracts as well as development of own assets.